Ledger.

Startup · $109m raised · Biotech and pharma

ENA Respiratory

Antiviral nasal spray to prevent severe respiratory viral infections

Melbourne, VIC

Coverage

Stories naming ENA Respiratory. Where several outlets covered the same round, they are bundled under whichever ran the fullest account.

Funding announcement

ENA Respiratory Begins Part B Dosing

Melbourne biotech ENA Respiratory has begun dosing participants in the second part of its Phase IIa trial of INNA-051; its investor lineup, past government funding awards and BLUE KNIGHT alumni status are recapped.

13 deals

Renewable Metals raises $12M Series A - Luan Atkinson, round details and contact

Profile of Australian battery-recycling company Renewable Metals, reporting its oversubscribed $12 million Series A with CEFC and Virescent Ventures leading, founder and CEO Luan Atkinson, and chair Peter Beaven.

12 deals

Brandon Capital's $60m taypayer-funded biotech bets

Brandon Capital has put roughly $60 million of National Reconstruction Fund money into ten biotech companies and warns R&D tax changes would hurt deep tech; portfolio company Myricx Bio went to Novartis.

Also australiatimes.com

Funding announcement

Six Australian infectious disease ventures share $10.48 million in funding round

An Australian infectious-disease incubator has selected six local biotechs to divide $10.48 million from its inaugural funding round, pairing non-dilutive cash with commercialisation support; the program is backed by an earlier MRFF grant.

News

ENA Respiratory Receives USPTO Notice of Allowance for Two Patents Covering TLR2 Agonists and Rhinovirus-Mediated COPD Exacerbations

Melbourne-based ENA Respiratory announced US patent allowances covering its TLR2 agonist platform and a COPD treatment method, strengthening IP protection for its INNA-051 nasal spray candidate now in Phase II testing.

News

ENA Respiratory Announces Dosing of First Participants in Phase II Study of INNA-051 Nasal Spray Designed to Protect Against Symptomatic Viral Respiratory Infections

Melbourne biotech ENA Respiratory has begun dosing volunteers in a mid-stage trial of its INNA-051 antiviral spray, aimed at limiting common viral illnesses in at-risk groups.

11 deals

Cheque-in: 8 startups raised $113 million this week to end October

Weekly funding roundup covering eight raises totalling over $113 million across aerospace, biotech, materials, health and software, plus a pharmacy firm's acquisition out of administration.

10 deals

Eight ANZ startups that raised $113 million this week

Weekly roundup of eight trans-Tasman startup raises worth a combined $113 million-plus, alongside Joe Zhou's buyout of StrongRoom AI from administrators.

Also Startup Daily·Startup Daily

5 deals

Uniseed boss Peter Devine calls time on 20 years leading Australia's OG VC

Uniseed chief executive Peter Devine departs after two decades; Monash's Alistair Hick takes over in 2026. The piece recounts Uniseed's fund history and recent stakes in ENA Respiratory and Morse Micro rounds.

News

Grit, strategy, and adaptability: the sportsmanship of biotech investing

A profile of Brandon Capital partner Chris Smith, tracing his path from immunology research and a Cambridge postdoc into biotech investing, with resilience lessons drawn from equestrian sport and companies Aravax and ENA Respiratory.

2 deals

ENA Respiratory Receives US$5m Investment from Flu Lab to Support Clinical Development of Novel Intranasal Antiviral Host Defence Immune Enhancer, INNA-051

Melbourne pharmaceutical company ENA Respiratory has received US$5 million from California's Flu Lab to advance clinical testing of its nasal immune-boosting antiviral candidate INNA-051.

Also Brandon Capital portfolio

3 deals

ENA Respiratory Announces Extension of U.S. Department of Defense Funding for Novel Prophylactic Antiviral

Melbourne's ENA Respiratory has won a further US$3.18 million US Defense Department contract to widen its INNA-051 Phase Ib trial to younger adults, extending the US$8.18 million the agency had already committed.

Also Brandon BioCatalyst portfolio·Brandon Capital portfolio·Brandon Capital portfolio·enarespiratory.com

8 deals

Funding Australia’s Future Economy: CUREator Deploys $7.21 Million to Propel local Life Sciences Potential

CUREator, Brandon BioCatalyst's government-backed grant program, has awarded $7.21 million across eight Australian biotech firms in its newest round, split between clinical-stage and preclinical recipients.

Also Brandon BioCatalyst portfolio·Startup Daily·ausceleratesa.org

Series A $12.5m

Melbourne AI startup set for global expansion after $12.5 million raise

AI search startup Marqo has landed a $12.5 million Series A and is relocating its headquarters to San Francisco, while LaunchVic statistics show Victoria's ecosystem grew in value despite a funding drop.

Funding announcement

Nasal Spray Significantly Accelerates Respiratory Virus Clearance in Phase 2a Clinical Study

Drug developer ENA Respiratory reports positive Phase 2a results for its INNA-051 nasal immunomodulator against influenza, with its Series A backed by Brandon Capital managed funds, the Minderoo Foundation and Uniseed.

Grant US$4.4m

ENA Respiratory Awarded $4.38 Million U.S. Department of Defense Agreement to Fund Development of Broad-Spectrum Antiviral INNA-051

ENA Respiratory receives a USD 4.38 million U.S. Department of Defense agreement to develop an intranasal dry powder antiviral; its past Series A backers are also recalled.

Also Brandon Capital portfolio

Funding announcement

ENA Respiratory Selected for BLUE KNIGHT™ to Accelerate Development of Pan-Antiviral Nasal Spray

Antiviral nasal spray developer ENA Respiratory has joined the Blue Knight program run by JLABS and BARDA, the first Australian company selected; background notes recall its Series A backing by Brandon Capital, Minderoo Foundation and Uniseed.

Funding announcement

ENA Respiratory Selected for BLUE KNIGHT™ to Accelerate Development of Pan-Antiviral Nasal Spray

Brandon Capital reports that ENA Respiratory has become the first Australian company chosen for BLUE KNIGHT, a JLABS-BARDA initiative supporting its intranasal broad-spectrum antiviral spray INNA-051.

News

First-in-Class, Broad-Spectrum Nasal Spray to Prevent COVID-19 and Other Common Respiratory Illnesses Set to Begin Phase 2 Trials

Biotech firm ENA Respiratory has contracted PPD and hVIVO to run Phase 2 trials of its INNA-051 nasal spray, which aims to prevent COVID-19 and other respiratory viral infections, after encouraging Phase 1 safety results.

News

First-in-Class, Broad-Spectrum Nasal Spray to Prevent COVID-19 and Other Common Respiratory Illnesses Set to Begin Phase 2 Trials

Biotech firm ENA Respiratory has contracted research organisations PPD and hVIVO to run Phase 2 trials of its INNA-051 nasal spray, following encouraging Phase 1 safety results, with participant recruitment expected from January 2022.

8 deals

The startup funding round: Digital ID verification, smart insurance, and nasal spray to protect against COVID-19

Weekly funding wrap covering several raises including Honey Insurance's record seed round, OCR Labs' Series A, and Ena Respiratory's COVID-19 nasal spray funding, plus Investible's second fund first close.

Also SmartCompany·Startup Daily·SmartCompany

2 deals

Australian spinout eyes the clinic with a prophylactic nasal spray for Covid-19

Australian biotech ENA Respiratory raised funding led by Brandon Capital and Minderoo Foundation to advance its Covid-19 nasal spray toward the clinic, and appointed Ruth Tal-Singer to its board.

Unnamed stage ≤$32m

ENA Respiratory Advances COVID-19 Preventative Therapy through AU$32 Million Fund Raise

ENA Respiratory secured up to AU$32 million, co-led by Brandon Capital Partners and Minderoo Foundation with Uniseed, to advance its INNA-051 nasal spray, and appointed Ruth Tal-Singer to its board.

Also Brandon Capital portfolio·Brandon BioCatalyst portfolio·Brandon Capital portfolio·Brandon BioCatalyst portfolio·Brandon Capital portfolio·Brandon Capital portfolio·SmartCompany·SmartCompany

6 deals

Brandon Capital news

Index of the venture firm's portfolio updates: financing rounds for AdvanCell and ENA Respiratory, grant awards via incubator programs, two closes of Fund Six, board hires, and Myricx Bio's completed sale to Novartis.

Also Brandon BioCatalyst portfolio·Brandon Capital portfolio·Uniseed·Brandon Capital portfolio·Brandon BioCatalyst portfolio·Brandon BioCatalyst portfolio·Brandon Capital portfolio·Brandon Capital portfolio·Brandon Capital portfolio·Cut Through Venture·SmartCompany·AFR Technology·Startup Daily·Startup Daily·SmartCompany·Startup Daily·Startup Daily·Startup Daily·@AuManufacturing·finance.yahoo.com·enarespiratory.com·Mirage News·Forbes Australia·advancell.com.au·Forbes Australia·datapile.co·Dealroom·Forbes Australia·datapile.co·Biotech Dispatch·fundedstartupsdaily.com·fundedstartupsdaily.com·Forbes Australia

Series A $11.7m

Nasal spray cuts COVID-19 growth, study shows

Ferret research found Ena Respiratory's INNA-051 nasal spray sharply lowered coronavirus levels; the biotech has banked an $11.7 million Series A and aims to begin human trials within months.

Also Brandon Capital portfolio·Brandon BioCatalyst portfolio·Brandon Capital portfolio·Brandon BioCatalyst portfolio·Brandon Capital portfolio

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